Aperito Journal of Pharmacology and Drug Designing

MOSES S. ELISAF

Professor of Medicine
Medical School
University of Ioannina
Address:Greece
Biography

Professor Elisaf was born in 1954 in Ioannina, Greece. He graduated from the School of Medicine, University of Athens in 1979.
He worked at the Institute of Lipids and Atherosclerosis Research, Sheba Medical Center, Tel Hashomer, Sackler School of Medicine, University of Tel-Aviv, Israel (1993-1994).
Currently, he is Professor of Internal Medicine in the University of Ioannina, Medical School (Ioannina, Greece) and Director of the 2nd Department of Internal Medicine and Division of Nephrology (University Hospital of Ioannina). He is also Head of the Lipids, Atherosclerosis, Obesity and Diabetes Department of the University Hospital of Ioannina. He has taken the Clinical Hypertension Specialist from the European Society of Hypertension.
He is an active member of about 27 medical societies, including the European Hypertension Society, European Atherosclerosis Society and the International Society of Hypertension. Additionally, he is the President of the Greek section of the American Society of Angiology. 
He is member of the Council of the Hellenic Atherosclerosis Society. He is Vice President of the Institute of Study, Research and Training for Diabetes Mellitus and Metabolic Diseases.
Professor Elisaf is editor in chief and member of the editorial board of 40 recognized medical journals. Furthermore, he is a referee of about 118 international medical journals.
He has organized many congresses and symposia in the field of Hypertension, Dyslipidemia, Atherosclerosis and Prevention of Cardiovascular Disease. He was the Chairman of the Satellite Meeting on Secondary Dyslipidemias of the European Atherosclerosis Society (EAS) 1999 symposium. He has participated in many International Multicentre Clinical Trials related to the treatment of hypertension, dyslipidemias, diabetes and other cardiovascular risk factors.
He has authored more than 600 peer-review papers in basic and clinical research in the field of Hypertension, Lipids and Atherosclerosis as well as Acid-base and Electrolyte Disorders.
He has organized and coordinated many educational seminars and scientific symposia on dyslipidemia, hypertension, diabetes, metabolic syndrome, Acid –base and Electrolyte Disorders etc.
He has participated as a conferrer as well as a speaker in many International, European and Greek congresses.
He has also authored three scientific text books for diagnosis and treatment of hypertension, dyslipidemias as well as electrolyte disorders.
Professor Elisaf is President of the Jewish Community of Ioannina and he was also President of the Cultural Center of the Municipality of Ioannina as member of the city Council.

Research Interests

DIABETES
METABOLIC SYNDROME 
LIPIDS
HYPERTENSION
ATHEROSCLEROSIS
ELECTROLYTE DISORDERS

Publications
Scientific Activities

KAUSHIK SHAHPhD

Research Associate
Department of Pharmaceutical
Texas Tech University Health Sciences Center
Address:United States
Biography

Dr. Kaushik Shah received his Ph.D in Pharmaceutical Sciences from Texas Tech University Health Sciences Center and M.S. in Pharmacology and Toxicology from National Institute of Pharmaceutical Education and Research. He is currently a Research Associate in the department of Pharmaceutical Sciences at Texas Tech University Health Sciences Center, Amarillo, Texas. Dr. Shah’s research focuses on the brain diseases/disorders with particular emphases on the impairment of nutrient/ion, drug transporters and metabolism. My objective is to evolve novel therapeutic targets and better therapeutic strategies with interdisciplinary approach to current health problems associated with brain especially in Stroke and Diabetes.

Research Interests

Blood Brain Barrier/ Neurovascular Pharmacokinetics
Stroke/Ischemia 
Neurodegneration
Neuroprotection
Neuropharmacology 
Nutrient and Ion Transporters
Diabetes

Publications
Scientific Activities

AzatMukhametovPhD

scientist
Computational/Physical Chemistry
Bashkir State University
Address:Russia
Biography

Dr. AzatMukhametovis a scientistin the fields of Computational/Physical Chemistry, Chemo- and Bioinformatics, and Molecular Modeling for Life Sciences. His research is devoted to application of computer technologies to bio-molecular and drug discovery challenges. 
During his career, Dr. AzatMukhametov has experienced in application of multiple commercial and open-source software to drug design, molecular modeling, virtual screening, molecular dynamic simulations, docking studies, homology modeling, and binding energy calculations. He is of the mind that computer technologies are the future of drug discovery, and his goal is to use them for creating real medicines.
He defended his Ph.D. degree in 2009 (Physical Chemistry, thesis “Design of chemical compounds with anti-inflammatory properties by the method of the theory of pattern recognition”).Had special post-graduate training in Germany financed by Honor Stipendium from the President of Russian Federation, in subject “Homology modeling of molecular structures of active and inactive conformations of Myt1 and Wee1 kinase, docking of ligands, MD simulations, and MM PB/GBSA free energy calculations”.During a postdoctoral training at the Centre of Chemical Biology (UniversitiSainsMalaysia), he applied methods of virtual screening, binding free energy calculations, and molecular modeling to study molecular mechanism of inhibition and discovery of new antiviral compounds against dengue and chikungunya viruses. At these days Dr. AzatMukhametovserves for an international pharmaceutical enterprise; at this role he provides consultancy and scientific support services to pharmaceutical and biotech companies, academic and non-profit institutions, and governmental bodies in the fields of his expertise.
Dr. AzatMukhametovhas received multipleawards for achievements in scientific research: Postdoctoral Fellowship Award from the University Sains Malaysia, Malaysia (2010-2013), Governmental Grant  from the Government of the Republic of Bashkortostan, Russian Federation (2008), Honor Stipendium from the President of Russian Federation (2007), Honor Ministry Stipendium from the Ministry of Natural resources of the Republic of Bashkortostan of Russian Federation (2007), Laureate of Nation-wide Competition for the best scientific work on medicinal chemistry among young scientists from the countries of former USSR (2007), Postgraduate Stipendium from the Ministry of Education of Russian Federation for postgraduate study (2005 – 2009).

Research Interests

Dr. AzatMukhametov is interested in design of bioactive chemical structures (chemicals and biologicals) with targeted properties; study, modeling, and simulation for life science molecular systems, macro- and micro- molecules; computational support for laboratory projects; catalytic and biophysical properties optimization for protein structures; virtual screening; prediction of pharmacological activity and ADME; full-cycle technologies from target to drug prototype; design and developing of network and desktop applications for life sciences; laboratory validations and support for drug discovery projects.

Publications
Scientific Activities

Ajaykumar N. SharmaPhD

Post-Doctoral Research Fellow
Dept. of Psychiatry & Behavioral Sciences
The University of Texas Health Science Center
Address:USA
Biography

Dr. Sharma has earned his doctoral degree in Biomedical Sciences from Boonshoft School of Medicine, Department of Pharmacology and Toxicology, Wright State University, Dayton, Ohio, USA. Dr. Sharma have vast experience in drafting research proposals, dissertations, scientific manuscripts, response to reviewers, abstracts, posters, reviewed scientific manuscripts and delivered poster and oral presentations at several national and international scientific sessions. Dr. Sharma also have a strong background in in-vivo and in-vitro experimental pharmacology and in-depth scientific training in rodent models for schizophrenia, depression, inflammation, anxiety, ethanol addiction, post-traumatic stress disorder, type-2 diabetes, epilepsy, obesity, and allergic disorders and research techniques such as HPLC, SDS electrophoresis, western blotting, ELISA, brain micro-punching, stereotaxic surgery, intracerebroventricular (icv) cannulation, EchoMRI and injection in rodents, isolation of various brain regions from rodent brain (amygdala, hippocampus, hypothalamus, frontal cortex etc), immunohisto/cytochemistry and adrenalectomy in rodents.

Research Interests

Dr. Sharma’s research interests include evaluating the role of hormones such as incretin analogues e.g. glucagon-like peptide-1(GLP-1) receptor agonist and dipeptidy-peptidase-IV (DPP-IV) inhibitor, insulin, progesterone and dehydroepiandrosterone sulphate (DHEAS), and neuroactive steroids e.g. allopregnanolone in major neuropsychiatric disorders and alcohol dependence. Moreover, his research is focused on investigating mechanisms for the co-morbidity between type II diabetes and major neuropsychiatric disorders such as depression, schizophrenia, anxiety and bipolar disorder.

Publications
Scientific Activities

Alexander E BerezinPhD

Professor of Medicine
Department of Internal Medicine
Zaporozhye State Medical University
Address:Ukraine
Biography

Dr. Alexander E. Berezin has received PhD in 1994 in the State Medical University of Zaporozhye (Ukraine). He is currently working as a Professor of Medicine in the State Medical University of Zaporozhye (Ukraine). As a Chief of Cardiology Unit of Internal Medicine Department, his research goals are fundamental study of biological markers, the implementation of visualization procedures and percutaneous cardiovascular interventions, the development of cardiovascular prevention and rehabilitation, especially in the field affected heart failure and coronary artery disease, as well as regenerative medicine. Based on this research and training in heart failure he has received several awards and honors, such as: Award of The Cabinet of Ministers of Ukraine (2002), Honor of The Ukrainian Cardiology Association (2004), and is serving one of the active members of the European Cardiology Society. He has authored more 550 research articles, 12 books/chapters. He is a fellow of the Ukrainian Cardiology Association; Member of the Ukrainian Heart Failure Association; Member of Heart Failure Association of the ESC; Member of European Acute Cardiovascular Care Association; Member of W.G. on Atherosclerosis and Vascular Biology of the ESC; Member of European Association of Percutaneous Cardiovascular Interventions; Member of European Association for Cardiovascular Prevention and Rehabilitation, Member of W.G. on Hypertension & the Heart of the ESC. He is current Editor-in-Chief of Biological Markers and Guided Therapy. He is serving as an editorial member of several reputed journals like Ukranian Medical J, J Cardiology and Therapy, Case Reports in Internal Medicine and expert Reviewers for journals like J Genetic Disorders and Genetic Reports; Obesity; Eur. J Clinical Investigations; J Food Science and Engineering; Case Reports in Internal Medicine; Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy; British Journal of Medicine and Medical Research; Biomarkers in Medicine; Pediatrics & Therapeutics; Journal of Vascular Medicine & Surgery; Journal of Pain & Relief; Cardiology and Angiology: An International Journal; Journal of Multiple Sclerosis; Journal of Clinical Case Reports; Journal of Haematology & Thromboembolic Diseases, Acta Biochimica et Biophysica Sinica; Journal of Gerontology & Geriatrics Research; Cloning & Transgenesis.

Research Interests

Cardiovascular disease
Biological markers
Metabolic comorbidities
Prognosis
Visualization procedures
Nuclear cardiology

Publications
Scientific Activities

CHANDISHWAR NATHPhD

Chief Scientist & Professor (AcSIR)
Division of Toxicology
CSIR-Central Drug Research Institute
Address:India
Biography

Dr Chandishwar Nath, Chief Scientist, & Professor (AcSIR) CSIR- Central Drug Research Institute, Lucknow, India obtained MD (Pharmacology) in 1978 from K. G. Medical College, Lucknow. He was Post Doctoral Associate in JH Miller Health Center, University of Florida, USA (1984-86) and Visiting Scientist- Medical Center, University of Arizona, USA (1991-92), Rudolf Magnus Institute of Neurosciences, The Netherlands (2003) and Institute of Clinical Pharmacology & Toxicology, Charite Medical University, Berlin (2010). He is a Fellow of National Academy of Medical Sciences (FAMS), Indian Pharmacological Society and Indian Academy of Neurosciences. He was awarded UVNAS PRIZE (1982), Prof Achari Oration (2006) and ICMR- Dr Prasad Oration (2007). He is a member of WHO Expert Committee on Drug Dependence, Advisory Committee for IND, Drug Controller General of India, Ministry of Health, Govt. of India and Research Council of CSIR-Indian Institute of Toxicological Research (IITR). The research work of Dr Chandishwar Nath on central neurotransmitter systems in Neurobehavioral disorders has received wide recognition.  He has 226 scientific publications and 9 International patents. There are more than 1700 citations of his research publications. His research group is currently working on molecular neuropharmacological aspects of memory functions, and conducted pioneer studies on Acetylcholinesterase enzyme and brain insulin receptors. His group is also involved in development of anti-dementia drugs of herbal origin. His research work may open new dimensions in understanding and treatment of memory dysfunctions.

Research Interests

Molecular neuropharmacological aspects of memory functions, and conducted pioneer studies on Acetylcholinesterase enzyme and brain insulin receptors.
Development of anti-dementia drugs of herbal origin.
Dimensions in understanding and treatment of memory dysfunctions.

Publications
Scientific Activities

Hak-Jae KimPhD

Assistant professor
Department of Clinical Pharmacology
Soonchunhyang University
Address:Korea
Biography

I took a Ph.D. degree of the Laboratory of Developmental Neurobiology, Kyung Hee University, Republic of Korea. My Ph.D. research focuses on psychiatric diseases, particularly schizophrenia, a population-based SNP (single nucleotide polymorphism) study of several diseases, the functional study of SNPs, and the study of related animal models. Thus far, the research that I have conducted on these subjects includes the following: a polymorphism (SNP, microsatellite, insertion/deletion, etc) study of various diseases, including psychiatric diseases, an investigation of antidepressants in the maternal separation model, and studies of the schizophrenia model induced by repeated MK801-treatment, prenatal stress, and prenatal inflammation. As an assistant professor for Dept. of Clinical Pharmacology of Soonchunhyng University, I have two main research themes. First of all, I have been studying candidate genes of schizophrenia and its roles in development of the disease. And also, genetic polymorphism studies of various diseases are conducting. In addition, I have research experiences about the mechanistic study of neurological and autoimmune disease such as rheumatoid arthritis. Based on these research themes, I published over 60 papers in SCI(E) journals from 2005

Research Interests

Neurobiology of Schizophrenia: NMDA receptor antagonism of schizophrenia
Animal model for schizophrenia
Population based genetic association study: Psychiatric diseases, Autoimmune diseases

Publications
Scientific Activities

Emanuele PetruzzellaPhD

Faculty of Medicine
Department of MedicineSchool of Pharmacy
Hebrew University of Jerusalem
Address:Israel
Biography

Dr. Petruzzella has received his Master Degree in Pharmaceutical Chemistry and Technology with a thesis in organic chemistry at Bari University, Italy, in 2009. Afterward, he obtained his Ph.D. in Applied Chemical and Enzymatic Synthesis at the same University with a thesis in bioinorganic chemistry in 2013. 
Dr. Petruzzella worked at Eastern Michigan University as postdoctoral research scholar from April 2013 to December 2014. In 2015 he moved to Israel, as postdoctoral research fellow at the Hebrew University of Jerusalem.
His doctoral and postodoctoral research activity has been focused on the discovery and development of new platinum-based antitumor drugs. He has synthesized and characterized several Pt(II) and Pt(IV) compounds and studied their stability and their reactivity toward biomolecules such as aminoacids, peptides,nucleotides and oligonucleotides, in order to clarify their mechanism of action and their metabolic fate.
He recently assayed the use of microwave technology for the synthesis of Pt complexes.

Research Interests

Synthesis and characterization of Pt(II) antitumor drugs and their Pt(IV) derivatives.
Study of the stability and reactivity of Pt compounds
Investigation of the interaction between biomolecules such as aminoacids, peptides, nucleotides and oligonucleotides.
Microvawe-assisted synthesis of Pt complexes.

Publications
Scientific Activities

V. JAYATHIRTHA RAOPhD

Head and Chief Scientist
Crop Protection Chemic
Indian Institute of Chemical Technology
Address:India
Biography

V. JAYATHIRTHA RAO has obtained his PhD (Prof. V. Ramamurthy) in 1983 from Department of Organic Chemistry, Indian Institute of Science, Bengaluru, India; Post Doctorate (Prof. R. S. H. Liu) 1983-1984 at University of Hawaii, Honolulu, USA and as Research Associate (Prof. Koji Nakanishi) 1985-1986 at Columbia University, New York, USA. He is Head and Chief Scientist of Crop Protection Chemicals Division of Indian Institute of Chemical Technology, Hyderabad, which is a premier R&D institute in India. He is a four time Alexander von-Humboldt Fellow - Germany. He visited Germany as panelist for Euro - India meeting (2011). He was visiting scientist at Tulane University, New Orleans-USA (1996-97) and also at University of Miami, Coral Gables, Florida – USA (2006-07). He is honored with Fellow of The Royal Society of Chemistry “FRSC” (London) in 2008. He is a Fellow of Andhra Pradesh Academy of Sciences “FAPAS” – Hyderabad. He is Fellow of the Indian Council of Chemists “FICC” - Agra. He is Fellow of The Indian Chemical Society “FICS” – Kolkatta. He is Member National Academy of Sciences “MNASc” – Allahabad.

Research Interests

Organic materials for applications in solar cells, light emitting devices
Synthesis of heterocycles for bioevaluation
Organic photochemistry - Academic
Method development for APIs – analytical studies
Process development and technology

Publications
Scientific Activities

Ki Churl ChangPhD

Vice president

Gyeongsang National University
Address:Korea
Biography

Bachalor (1975) Sungkyunkwan University, College of Pharmacy, Seoul, Korea
Master (1982) Seoul National University, College of Medicine, Seoul, Korea
PhD (1984) Seoul National University, College of Medicine, Seoul, Korea
Post doc (1988-1989) University of Cincinnati, Department of Pharmacology and Molecular Biophysics, OH, USA
Visiting Professor (1994-1995) Tokyo University, School of Veterinary Medicine, Department of Pharmacology
Research Scientist (1997) The William Haevery Research Institute, UK

Research Interests

Cardiovascular pharmacology
Heme oxygenase related pharmacology
Inflammation, cancer and transcription
Intensive care medicine, sepsis

Publications
Scientific Activities

BERRO, Laís Fernanda


Department of Psychobiology, Sleep Division
Universidade Federal de São Paulo (UNIFESP)
Address:Brazil
Biography

Lais F. Berro received her Biomedical Sciences degree and Master’s degree in Psychobiology from the Federal University of São Paulo (Universidade Federal de São Paulo, UNIFESP, São Paulo, Brazil). Mrs Berro has experience in the fields of sleep biology and sleep medicine, studying behavioral neuropharmacology with focus on the interaction between drug addiction and sleep. Recent efforts have focused on the modulation of the dopaminergic reward system by sleep conditions.

Research Interests

Sleep biology
Sleep medicine
Studying behavioral neuropharmacology
Modulation of the dopaminergic reward system by sleep conditions

Publications
Scientific Activities

Mahmoud M. El-MasPhD

Chair & Professor
Department of Pharmacology and
Distinguished Research Professor of Alexandria Uni
Address:Egypt
Biography

B.S. Pharmacy 1982, M.S. 1986, PhD 1990. Full professor of Pharmacology 2000; Chair, Dept. of Pharmacology, Pharmacy, Alexandria Univ.; Chair, National Scientific Committee on Faculty Promotion (Pharmacology and Clinical Pharmacy). Graduate student, Leeds Univ. (1988-1990), visiting research scholar, East Carolina Univ., NC, USA. (1991-1993, 1996-1999, 2002-2004). Publications: 99 peer-reviewed scholarly articles published in top tier international journals and 79 abstracts in international conferences. Research expertise: cardiovascular and renal neurobiology of drugs of abuse (ethanol, nicotine) and immunosuppressants. Editorial board positions: Naunyn-Schmiedeberg's Archives of Pharmacology, ChronoPhysiology and Therapy, Pharmacy Times Middle East, African journal of Pharmacy and Pharmacology, Edorium Journal of Pharmacology, Austin Journal of Vascular Medicine, the Open Access Journal of Science and Technology. Awards: The National Prize for Scientific Encouragement (twice), The National Prize for Scientific Excellence, ACDIMA award (Jordon), Alexandria University Honorary Award, Distinguished Research Professor of Alexandria Univ., The Silver and Gold Appreciation Medal Awards (General Syndicate of Pharmacists, Egypt).

Research Interests

Cardiovascular
Renal neurobiology

Publications
Scientific Activities

PALANISAMY SANKARPhD

Assistant Professor
Veterinary Pharmacology and Toxicology
Deemed University, Indian Veterinary Research Inst
Address:India
Biography

Dr. P. Sankar obtained his Ph.D from Deemed University, Indian Veterinary Research Institute (IVRI), Izatnagar, Bareilly, India where he also received his Masters’ degree in Veterinary Pharmacology and Toxicology. He joined the Division of Pharmacology and Toxicology, IVRI where he worked as a scientist. In July, 2013 he moved TANUVAS, where he presently serve as the Assistant Professor.

Research Interests

Toxicodynamic interactions of different type of environmental pollutants and xenobiotics
Isolation and characterization of active principles as therapeutic measures for different type of environmental pollutants-induced toxicity
Development of different type of nanoparticle-based drug delivery system for prevention of different type of environmental toxicity

Publications
Scientific Activities

Priyanka TrivediPhD

Postdoctoral Fellow
Biochemistry and Molecular Biology
Mayo Clinic
Address:Maricopa
Biography

Priyanka Trivedi is a Postdoctoral Research Fellow at Mayo Clinic, Scottsdale, AZ, USA. Her research area involves vaccine-based cancer immunotherapy. She is involved in studying the role of MUC1, a mucin that is over-expressed and aberrantly glycosylated in various types of cancer, in tumor progression, metastasis and modulation of the immune system. She would like to discover the basic mechanisms involved in the pathogenesis of carcinogenesis and the ways to prevent the progression of carcinogenesis to benefit mankind. She pursued her Ph.D. in Pharmacology and Toxicology and M. S.(Pharm.) in Regulatory Toxicology at the National Institute of Pharmaceutical Education and Research (NIPER), Mohali, Punjab, India. Her doctoral research was mainly focused on elucidating the molecular mechanisms involved in ulcerative colitis-associated local damage and extra-intestinal manifestations as well as colitis-associated colon carcinogenesis. During her masters, she was involved in several kinds of pre-clinical toxicity studies at the National Toxicology Center of NIPER. She is a winner of Carl C. Smith Graduate Student Award, 2nd place, Mechanisms Specialty Section of Society of Toxicology (SOT) during the 53rd annual meeting of SOT (Year 2014) at Phoenix, AZ, USA. She is also a winner of the Ranbaxy Science Scholar Award-2013. She is a member of various scientific societies such as American Association of Cancer Research (AACR), Society of Toxicology-USA (SOT), American College of Toxicology (ACT), Society of Toxicology-India (STOX) and Inflammation Research Association (IRA). She has authored many research and review articles and has served as a reviewer for various renowned journals.

Research Interests

Vaccine-based cancer immunotherapy
Ulcerative colitis
Molecular toxicology
Pre-clinical toxicology (genotoxicity, carcinogenesis, hepatotoxicity, cardiotoxicity, nephrotoxicity, germ cell toxicity, reproductive toxicology)
Pre-clinical drug development 
Regulatory toxicology
Risk assessmen

Publications

1. Shreyas Jadhav, Jenifer Sematti, Amrendra Kumar Ajay, Trivedi PP, Kathryn Pelligrini, Florin
Craciun, Vishal S. Vaidya. RNA binding protein Musashi homologue 1 regulates kidney fibrosis
by translational inhibition of p21 and Numb mRNA. J Biol Chem. 2016: In press (PMID:
27129280).
2. Lakshminarayanan V, Supekar NT, Wei J, McCurry DB, Dueck AC, Kosiorek HE, Trivedi PP,
Bradley JM, Madsen CS, Pathangey, Hoelzinger DB, Wolfert MA, Boons GJ, Cohen PA, Gendler
SJ. MUC1 vaccines, comprised of glycosylated or non-glycosylated peptides or tumor-derived
MUC1, can circumvent immunoediting to control tumor growth in MUC1 transgenic mice.
PlosOne 2016: 11: e0145920.
3. Trivedi PP, Jena GB, Tikoo KB, Kumar V. Melatonin modulated autophagy and Nrf2 signaling
pathways in mice with colitis-associated colon carcinogenesis. Mol Carcinog. 2016: 55: 255-267.
4. Namoju RC, Khan S, Patel RS, Shera FY, Trivedi PP, Kushwaha S, Jena GB. Pre-pubertal
exposure of cytarabine-induced testicular atrophy, impaired spermatogenesis and germ cell DNA
damage in SD rats. Toxicol Mech Methods 2014: 24: 703-712.
5. Parmar AR, Trivedi PP, Jena GB. Dextran sulfate sodium-induced ulcerative colitis leads to
testicular toxicity in mice: Role of inflammation, oxidative stress and DNA damage. Reprod
Toxicol. 2014: 49: 171-184.
6. Trivedi PP, Jena GB. Mechanistic insight into beta-carotene-mediated protection against
ulcerative colitis-associated local and systemic damage in mice. Eur J Nutr. 2015: 54: 639-652.
7. Trivedi PP, Jena GB. Melatonin reduces ulcerative colitis-associated local and systemic damage
in mice: Investigation on possible mechanisms Dig Dis Sci. 2013: 58: 3460-3474.
8. Trivedi PP, Jena GB. Role of alpha-lipoic acid in dextran sulfate sodium-induced ulcerative
colitis in mice: Studies on inflammation, oxidative stress, DNA damage and fibrosis. Food Chem
Toxicol. 2013: 59: 339-355.
9. Ramanjaneyulu SVVS, Trivedi PP, Kushwaha S, Vikram A, Jena GB. Protective role of
atorvastatin against doxorubicin-induced cardiotoxicity and testicular toxicity in mice. J Physiol
Biochem. 2013: 69: 513-525.
10. Trivedi PP, Jena GB. Ulcerative colitis-induced hepatic damage in mice: Studies on
inflammation, fibrosis, oxidative DNA damage and GST-P expression. Chem Biol Interact. 2013:
201: 19-30.
11. Trivedi PP, Jena GB. Dextran sulfate sodium-induced ulcerative colitis leads to increased
haematopoiesis and induces both local as well as systemic genotoxicity in mice. Mutat Res. 2012:
744: 72-183.
12. Khan S, Ahmad T, Parekh CV, Trivedi PP, Kushwaha S, Jena GB. Investigation on sodium
valproate induced germ cell damage, oxidative stress and genotoxicity in male Swiss mice.
Reprod Toxicol. 2011: 32: 385-394.

13. Kushwaha S, Vikram A, Trivedi PP, Jena GB. Alkaline, Endo III and FPG modified comet assay
as biomarkers for the detection of oxidative DNA damage in rats with experimentally induced
diabetes. Mutat Res. 2011: 726: 242-250.
14. Trivedi PP, Kushwaha S, Tripathi DN, Jena GB. Cardioprotective effects of hesperetin against
doxorubicin-induced oxidative stress and DNA damage in rat. Cardiovasc Toxicol. 2011: 11: 215-
225.
15. Trivedi PP, Tripathi DN, Jena GB. Hesperetin protects testicular toxicity of doxorubicin in rat:
Role of NFκB, p38 and caspase-3. Food Chem Toxicol. 2011: 49: 838-847.
16. Trivedi PP, Kushwaha S, Tripathi DN, Jena GB. Evaluation of male germ cell toxicity in rats:
Correlation between sperm head morphology and sperm comet assay. Mutat Res. 2010: 703: 15-
121.
Peer Reviewed Review Articles
1. Dadhania VP, Trivedi PP, Vikram A, Tripathi DN. Nutraceuticals against neurodegeneration: a
mechanistic insight. Curr Neuropharmacol. 2015: In Press.
2. Jena GB, Trivedi PP. A review of the use of melatonin in ulcerative colitis: Experimental
evidence and new approaches. Inflamm Bowel Dis. 2014: 20: 553-563.
3. Jena GB, Trivedi PP, Sandala B. Oxidative stress in ulcerative colitis: An old concept but a new
concern. Free Radic Res. 2012: 46: 1339-1345.
4. Jena GB, Trivedi PP. Role of autophagy in inflammation and cancer: the concept of survival and
death. Curr Res Info Pharm Sci. 2012: 13: 10-14.
5. Jena GB, Trivedi PP, Mughal A. The Application of the Principles of Good Laboratory Practice
(GLP) in Regulatory Toxicity Studies. Curr Res Info Pharm Sci. 2009: 10: 25-28.

Scientific Activities

Akram Ranjbar

professor in Dept of Toxicology &Pharmacology
Faculty of Pharmacy Hamadan university of Medical
Hamadan
Address:Iran
Biography
Research Interests

Biochemical toxicology (oxidative stress)
Mechanisms of toxicity
Pesticides
Phosphodiestrase inhibitors drugs
Nonotoxocology

Publications
Scientific Activities

RICCARDI CARLOPhD

Director
Department of Medicine
Section of Pharmacology
Address:Italy
Biography

Carlo Riccardi is Professor of Pharmacology and Director of Dept. of Medicine at University of Perugia. He graduated in Pharmacy and in Medicine from University of Perugia. He serves as Professor of Pharmacology at School of Medicine at University of Perugia. He is member of Nominating Committee of IUPHAR and board member of Immunopharmacology Section of IUPHAR. 2009-2011 President, Italian Society of Pharmacology (SIF). 1981 Consultant, National Cancer Institute, N.I.H., Bethesda, Maryland, U.S.A. 1978 Guest Visitor, Laboratory of Immunodiagnosis, N.C.I., N.I.H., Bethesda, Maryland, U.S.A. 1975-1976 Research Associate, Dept. of Pathology, State University of New York at Buffalo, Buffalo, N.Y., U.S.A. 
Prof. Riccardi is author of more than 230 publications including articles in peer reviewed international journals and scientific books. His main research interest is immunology and immunopharmacology, with particular interest in the glucocorticoid (GC) role in regulation of autoimmune/inflammatory diseases. In particular, at the beginning of his career, he studied the natural immune response mediated by Natural Killer (NK) cells by giving proof of their in vivo activity. He then began studies on GC and discovered two glucocorticoid-induced gene: glucocorticoid-induced leucine zipper (GILZ) and Glucocorticoid-induced Tumor Necrosis factor Receptor family related gene (GITR). He also studied the mechanisms of GC involved in the regulation of proliferation and apoptosis in normal and neoplastic cells. His present research covers all aspects of GC, GILZ and GITR biology including the role in regulation of cell growth and differentiation and in human inflammatory diseases.

Research Interests

Immunology and immunopharmacology, with particular interest in the glucocorticoid (GC) role in regulation of autoimmune/inflammatory diseases

Publications
Scientific Activities

Rodrigo Gimenez Pissutti Modolo

Interventional Cardiology in Laboratory of Card
University of Campinas (UNICAMP)
Researcher at UNICAMP
Address:Brazil
Biography

Dr. Rodrigo Modolo has received his MD degree and performed his fellowship in internal Medicine in Federal University of Uberaba (UFTM – Brazil). Later has performed his cardiology and interventional cardiology fellowships in the University of Campinas (UNICAMP – Brazil). Also received his PhD degree in cardiovascular Pharmacology in UNICAMP. Now he is acting as a staff of Cardiology in the University Hospital (Clinics Hospital of UNICAMP), in Campinas, Brazil, and also as Interventional Cardiologist in the same Hospital. Currently with over 18 research/review articles in cardiology and cardiovascular medicine. Acting as a researcher in the field of pharmacology and cardiology, with interests in Resistant Hypertension, atherosclerosis, interventional cardiology, drugs in cardiology, and cardiovascular imaging.

Research Interests

Resistant hypertension
Interventional cardiology
Cardiovascular pharmacology
Cardiology / Atherosclerosis / Ischemic heart disease
Diabetes
Image diagnostic methods in cardiology

Publications
Scientific Activities

SALEEM FAROOQPhD

Research Scholar
Bio-Organic Chemistry Division
Indian Institute of Integrative Medicine
Address:INDIA
Biography

Saleem Farooq, presently working as research scholar at Indian institute of Integrative Medicine-Jammu (CSIR). I had the opportunity to go through your pioneering research publications in the area of organic synthesis, synthesis of complex carbogenic molecules, chemical biology interface / medicinal chemistry which prompted me to write this letter to you, with a view to explore the possibility of working as a post doctoral fellow in your esteemed research group. I completed my graduate studies at Indian institute of Integrative Medicine-Jammu (CSIR) and got my Ph.D degree in the year 2013 for my thesis entitled Bio-prospection of natural products and synthesis of bioactive molecules for lead development and generation of novel synthetic methodologies

My current research mainly focuses on Design and Synthesis of library of Piperine Mimics as Multidrug Efflux Pump Inhibitors. Earlier in my Ph.d program my work was focused on design and synthesis of target based anticancer therapeutics including development of novel hybrid molecules, synthesis of drug libraries based on natural products scaffolds (couramins) and development of new synthetic methodologies. In addition to my basic research I have worked in various sponsored project of the institute simultaneously. My knowledge and experience in synthetic / Medicinal Chemistry for more than four year have enhanced my ability to work productively in a competitive environment and would definitely assist in research program.

Research Interests

Design and Synthesis of library of Piperine Mimics as Multidrug Efflux Pump Inhibitors
Anticancer therapeutics
Synthesis of drug libraries based on natural products scaffolds

Publications
Scientific Activities

Sinan INCEPhD

Associate Professor
Department of Pharmacology and Toxicology
University of Afyon Kocatepe
Address:TURKEY
Biography

Sinan Ince is an Associate Professor in the Department of Pharmacology and Toxicology at the University of Afyon Kocatepe where he has been a faculty member since 2001. Sinan completed his Ph.D. at Ankara University. His research interests lie in the area of xenobiotics and its toxic effects on tissue and organism. Also, he investigated effects of elements, especially boron, on tissue morphology, moleculer and biochemical mechanism. He has collaborated actively with researchers in several other disciplines of biological science. Sinan has participated on roughly thirty conference and workshop program committees. He currently serves on the Editorial Board of many scientific journals. Sinan has taught pharmacology and toxicology on undergraduate topics in veterinary medicine. In his ever-vanishing spare time, Sinan enjoys playing (poorly) and watching football, (road) bicycling, and enjoying good food, and live theatre.

Research Interests

Pharmacology, especially pharmacodynami
Toxicology, especially in vitro embryo toxicity
Oxidative stress, lipid peroxidation, and antioxidant capacity

Publications
Scientific Activities

Vinod KumarPhD

Assistant Professor in the Central University of P
Centre for Chemical and Pharmaceutical Sciences

Address:India
Biography

Dr. Vinod Kumar is currently working as Assistant Professor in the Central University of Punjab, Bathinda, India. He has done his PhD from Institute of Himalayan Bioresource Technology, Palampur with affiliation from Guru Nanak Dev University Amritsar in 2007. Subsequently, he pursued postdoctoral studies at Siena University Italy with Prof. G. Campiani and worked there for two years. In Siena University he worked independently on two different projects involving design and synthesis of anticancer and antipsychotic compounds. Thereafter he moved to United Kingdom and joined Professor Stephen Husbands’s research group at Bath University. In this lab Dr. Kumar worked on the synthesis of ligands having relative selectivity for different opioid receptors. His current research interests are in the field of design and synthesis of heterocyclic ligands for colchicine binding domain and their screening for anticancer activities. In addition Dr. Kumar is also working on Monoamine Oxidase inhibitors and investigating their role in various neurogenic disorders.

Research Interests

Pharmacology & Drug Designing

Publications
Scientific Activities

Amer Zeidan

Assistant Professor of Medicine
Department of Internal Medicine
Yale University
Address:New Haven, CT
Biography
Research Interests
Publications
Scientific Activities

ARTURO RAMON ANADON NAVARRO

Assistant and Associate Professor of Pharmacology
Departamento de Toxicolog y Farmacology
Universidad Complutense de Madrid
Address:Spain
Biography

Dr. Arturo Anadón has authored and/or co-authored over 200 scientific articles on issues concerning pharmacology, molecular toxicology, pharmacokinetics, Toxicokinetics, therapeutics, residues in food producing animals and regulatory matters in the journals including Journal of Physiology (London), Toxicon, Archives Internationales de Pharmacocynamie et de Therapie, Naunyn-Schmiedeberg’s Archives of Pharmacology, Veterinary and Human Toxicology, Annales des Recherches Veterinaires, Journal of Veterinary Pharmacology and Therapeutics, Revue de Médicine Vétérinaire, Avian Pathology, American Journal of Veterinary Research, Bulletin de l’Academie Vétérinaire de France, Bulletin of Environmental Contamination and Toxicology, Antimicrobial Agents and Chemotherapy, Archives of Toxicology, Toxicology and Applied Pharmacology, Research in Veterinary Science, The Veterinary Record, Toxicology and Industrial Health, Regulatory Toxicology and Pharmacology, Reviews of Environmental Contamination and Toxicology, Journal of Food Protection, Food and Chemical Toxicology, The Veterinary Journal, Toxicology Letters, Journal of Agricultural and Food Chemistry, European Food and Feed Law Review, Medicina Clinica (Barc.), Journal of Chromatography B Expert Opinion on Drug Metabolism and Toxicology, Toxicology in Vitro, Toxicology, and Mutation Research - Genetic Toxicology and Environmental Mutagenesis, BMC Pharmacology and Toxicology among others, and more 100 chapter books.

Research Interests

Pharmacology /Toxicology
Pharmacokinetics / Toxicokinetics
Drug Metabolism
Molecular Toxicology
In vivo/ In vitro toxicology
Clinical Toxicology and Pharmacology
Neurotoxicology
Residues of veterinary drugs in animal products
Food Toxicology
Risk assessment
Drug regulations

Publications
Scientific Activities

Beibei HuangPhD

Postdoctoral Scholar
Metabolic Flux Analysis
University of California
Address:United States
Biography

Beibei Huang is a postdoctoral fellow at QB3, University of California Berkeley. She received her PhD degree in Pharmaceutical from Second Military Medical University in 2009. She received numerious Awards, including National Youth Scholar Award from National Natural Science Foundation of China, Early Career Award from Shanghai Science and Technology Committee, etc. She is a member of American Chemical Society.

Research Interests

Natural product analysis
Mass spectrometry
Chromatography
Metabolic flux and other Molecular biology.

Publications
Scientific Activities

Li JianjunPhD

Professor
Wuhan University School of Medicine

Address:India
Biography

Li Jianjun 1975-1978 Hubei countryside youth, 78, was admitted to Wuhan University School of Medicine (formerly Hubei Medical College), were awarded a master's degree and a Bachelor of Medicine Department of Cardiology in 1983 and 1986. 1991 Japan selected by the State Board of Education study, 95 was awarded a doctorate in cardiovascular Kyushu University in Japan, 1995-1997, to do postdoctoral work at the United States Department of Cardiology, University of Louisville Louis Grand. 1997 appointed Professor of Cardiology, People's Hospital of Wuhan University. 2003 appointed deputy director of the First Affiliated Hospital of Tsinghua University Heart Center, 2004 -2011 he was appointed deputy director of the National Cardiovascular Center Fu Wai Hospital coronary heart center, 2011 has dyslipidemia and cardiovascular disease treatment center and clinics Director of the Centre, 25B ward, chief physician, professor and doctoral tutor.

Research Interests

The main research direction is abnormal lipid metabolism and atherosclerosis, inflammatory diseases, relationships with, mainly related to the pathogenesis of coronary heart disease and related therapy. In the research is completed and provincial research 16 (National Natural Science Foundation of China 3). Social work, including more than 10 types of cardiovascular domestic magazine deputy editor, managing editor and editorial board, five kinds of international journals and more than 20 kinds of international editorial board of the journal invited reviewers, the National Natural Science Foundation of judges. National Science Progress Award 1, Hubei Provincial Science Progress Award 4. Published more than 350 papers, including SCI source journals published more than 180 papers, impact factor total score of 400 points (including communications and / or the first of more than 130 articles, impact factor total score of 250 points). 2008, 2009 and 2011, respectively, was published in the United States "Who's Who in the World", "Who's Who in Medicine and Healthcare" and Cambridge "2000 Outstanding Intellectuals of the 21st Century" collection. Coronary heart disease (including interventional treatment), diagnosis and treatment of hyperlipidemia, hypertension and other cardiovascular diseases have more experience.

Publications
Scientific Activities

Harish AroraPhD

Assistant professor
Pharmaceutical Chemistry
Guru Jambheshwar University Of Science & Technolog
Address:India
Biography

Harish Arora, PhD in department of Pharmaceutical sciences, Guru Jambheshwar University of Science & Technology, Hisar, I have completed my M.Pharm (Pharmaceutical Chemistry) from Guru Jambheshwar University of Science & Technology, Hisar (2009-2011), Professional Diploma in Clinical Research (2007), Diploma in Scientific writing and creation of essential documents (2011), Diploma in Oncology Clinical Trials Training (2012) from Catalyst Clinical Services Pvt. Ltd. New Delhi.Done my PhD in Pharmaceutical Sciences at Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science & Technology, Hisar and Diploma in Project Management from Catalyst Clinical Services Pvt. Ltd. New Delhi. Besides this, I have completed more than 15 Online Pharmaceutical Industrial Courses/E-courses from National Institute of Health, USA, Food and Drug Administration USA (US FDA), Biopharma institute New Jersey. All the online courses were evaluated based upon regular online study followed by a series of online tests held in Feb 2012. I have also worked as an Assistant professor in Shri Ram college of Pharmacy, Karnal (Haryana) from Sept 2011 to Jan 2012 and Aug 2012 to dec 2013. I have presented Papers, Posters, delivered Powerpoint Presentations all over India and have delivered guest lecture in a seminar held recently at Manav institute, Jevra (Hisar). I am the Member of Editorial Board and Reviewer of Six Renowed Journals. I am presently running "Pharma Train"- an international community, for the benefits of Pharma professionals. I have been appointed as the President of Haryana State for Future Pharmacist welfare association of India (FPWAI)-An involuntary association working for Pharma professionals and young Pharmacists. I am the founder and Director of International Pharmaceutical Writers association 9 (IPWA). recently i have published my Book on Pyrazoles in lambert Publishers, Germany. I believe that my qualification along with my positive attitude makes me a perfect candidate for the employment in your esteemed organization.

Research Interests

Medicinal Chemistry, Drug Discovery and Development
Synthetic, Organic and Analytical Chemistry
In-Silico drug design and Molecular Modelling (CADD)
NMR, IR and Mass spectra interpretation
Docking Studies, Combinatorial synthesis, QSAR, Drug-receptor interaction studies
Computational analysis & Pharmaceutical Analysis
Pharmacovigilance, Clinical Research and New Drug Development Process
Scientific Writing and Creation of Essential documents
Oncology clinical trials

Publications
Scientific Activities

Kiran Kumar Bali


Institute for Pharmacology
Heidelberg University
Address:Germany
Biography
Research Interests
Publications
Scientific Activities

Kulbhushan SharmaPhD

Scientist INMAS
Division of Radiation Biosciences
Institute of Nuclear Medicine and Allied Sciences
Address:India
Biography

I have completed my PhD in the area of Molecular Biology in August 2008 under the supervision of Dr. Sunil Lal in the Virology group at International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi, India. Now, I am working as a scientist in one of the Govt organizations in India and I am interested to join your lab as a postdoctoral fellow. My doctoral research titled "Protein-protein and RNA-protein interaction of SARS coronavirus" emphasized on protein-protein interactions. I analyzed the ability of 3a protein of SARS Coronavirus to interact with its 5'UTR region and non-structural proteins nsp8 and nsp9. I explored the formation of a ternary complex between 3a-nsp8 and nsp9. We, in collaboration with HKU have confirmed the role of this ternary complex in viral-replication. Although not included in my thesis, I have also worked on signaling pathways induced by H5N1 virus during my Ph.D. In another study on 9b protein (an accessory protein of SARS-CoV), I found that it forms a dimer with its N-terminus region. Also, it enters passively into the nucleus and comes out using its NES. Thus, I have gained experience on protein transport pathways too. Most of these studies have already published in per reviewed journals. In order to continue the work I initiated on H5N1 virus during my Ph.D., I joined as research associate in the same lab after completion of my doctorate research. Here, I performed yeast two hybrid screening using human lung library against NP protein of this virus and found some interacting partners. In collaboration with Dr. Nancy Cox group at CDC, Atlanta, we found that H5N1 (and H1N1), using its interaction with hsp40 (a chaperone protein) affect some important signaling pathways and keeps translational machinery "ON" so that the virus can survive. Another interacting partner for nucleocapsid protein of H5N1 was clusterin, an anti-apoptotic gene. Since my initial exposures to the field of molecular biology, I had immense interests on exploring cancer signaling and the survival pathways. Since Sep 2009, I am working as a scientist in one of the laboratories in India. I have been trying to understand the molecular mechanism of cellular transformation on exposure to carcinogens. We are currently working on the role of prostaglandins in this mechanism. We are trying to understand COX-2 signaling and looking into some novel targets for cancer therapeutics. We have found some very interesting results using PGE2, an intermediate in COX-2 signaling.

Another very interesting area of my research is understanding the recycling mechanism, Autophagy. We are trying to understand every aspect of this mechanism starting from its basic mechanism and functional contribution. We are using several markers including GFP tagged markers (LC3-II, p62, other Atgs), biochemical techniques as well as electron microscopy to understand the same. Our long term goas include a clear understanding of the exact link between oxidative stress, ER stress, calcium signaling, mitochondrial biogenesis and autophagy. Our initial finding are very exciting and clearly indicate autophagy and mitophagy as survival mechanisms.

Research Interests

Exploring cancer signaling and the survival pathways
Molecular mechanism of cellular transformation on exposure to carcinogens
Prostaglandins in this mechanism

Publications
Scientific Activities

Leila Safaeian

Assistant Professor of Pharmacology
Faculty of Pharmacy and Pharmaceutical Sciences Isfahan
University of Medical Sciences
Address:Iran
Biography

Dr. Safaeian is an Assistant Professor of Pharmacology at the Isfahan University of Medical Sciences, School of Pharmacy and Pharmaceutical Sciences, Iran. She is the Director for the Research & Development Department, Food and Drug Deputy, Isfahan University of Medical Sciences. She has been authored and co-authored for 30 articles, and is a reviewer of 10 journals.

Research Interests

Her previous research activities had focused on pharmacological researches on animal models of pulmonary fibrosis and her recent investigations are often based on Pharmacological researches on animal models of hypertension, Evaluation of oxidative stress in plasma and Human Umbeliferal Vein Endothelial Cell (HUVEC), Rational Usage of Drugs and Prescription Patterns

Publications
Scientific Activities

MANICKAM SIVAKUMARPhD

Professor
Department of Chemical and Environmental Engineering
University of Nottingham Malaysia Campus
Address:Malaysia
Biography

Professor Sivakumar Manickam (Siva) is a Chemical Engineer specializing Process Engineering of Nanomaterials especially Nanopharmaceuticals. He is working in the area of Ultrasound and Hydrodynamic Cavitation. He has graduated from UDCT, Mumbai, India. Presently he is working with University of Nottingham, Malaysia campus and his research group concentrates on the process development of cavitation based reactors towards technologically important nanomaterials. He is also heading the Manufacturing and Industrial Processes Research Division and is the Coordinator of the Centre for Nanotechnology and Advanced Materials. He was also the recipient of JSPS fellowship, Japan. He has published ~170 peer reviewed journal and conference papers. He is the Fellow of Higher Education Academy (UK) and member of Institute of Nanotechnology (IoN).

Research Interests

Nanoengineering of Advanced Materials (Synthesis, characterization and process development)
Utilisation of highly Energy Efficient Cavitation Technique and Transformation of the same from Lab to Pilot scale for the Synthesis of Nanomaterials and wastewater treatment
Development of Nanosuspensions and Nanoemulsions for Pharmaceutical Industries
Exploitation of Novel Carbon Nanomaterials such as Graphene, CNTs and Fullerenes for Drug Delivery and Nanobiosensor.

Publications
Scientific Activities

Mayur M. PatelPhD

Associate Professor
Department of Pharmaceutics
Nirma University
Address:India
Biography

Dr. Mayur Patel, Associate Professor in Department of Pharmaceutics, has 8 years of teaching experience. He has completed M.Pharm. and Ph. D. from Institute of Pharmacy, Nirma University. He has Nineteen International and National Publications to his credit with total impact factor of more than 45, total citations more than 400 and ‘h’ index of 10. He is a recipient of minor research project of worth Rs. 4 lacs from Gujarat Council on Science and Technology (GUJCOST). He is reviewer for many high impact factors journals of publishers like Informa Healthcare Ltd., American Chemical Society (ACS), SAGE, Bentham Science, etc. to name a few. He has attended many International and National level conferences and participated in State level Paper Presentation competition. He has been an author and coauthor of more than 60 papers (both research and review) presented at state, national and international level seminars and conferences. He got first prize in the National level poster presentation competition. He also got first prize in NIRMAQUEST 2005 (A State level Quiz and Elocution Competition for Pharmacy students). He has been invited to deliver lecture as a Resource Person at AICTE sponsored Two weeks Staff Development Programme. He is a life member of Professional bodies like APTI, IPA, IHPA, SOPI, ISTE and IPGA. He has authored books on “Practicals in Pharmaceutical Analysis – I” and “A Text-book of Hospital Pharmacy”. He has also written a book chapter on “Drug Delivery: Oral Colon-Specific” in Encyclopedia of Pharmaceutical Science and Technology, 4th Edition, 2013, Published by Informa Healthcare Inc. UK. He is a recognized PG and Ph.D. guide at Nirma University. His area of interest is Novel Drug Delivery Systems.

Research Interests

Novel Drug Delivery Systems

Publications
Scientific Activities

Rafik Karaman PhD

Professor
Pharmacology
College of Pharmacy, Al-Quds University
Address:Palestine
Biography

Professor Rafik Karaman is currently a Distinguished professor of pharmaceutical sciences, College of Pharmacy, Al-Quds University, Jerusalem, Palestine. He received his Ph.D. degree in bioorganic chemistry from the Hebrew University in 1987, his MS degree in Pharmaceutical Sciences from the Hebrew University in 1983, and his bachelor’s degree in Pharmacy from the Hebrew University in 1981. He was an Assistant Professor at the University of Toledo and University of California at Santa Barbara for 5 years where he worked with Professor T.C.Bruice in the bioorganic chemistry field. Professor Karaman is broadly interested in the design and synthesis of prodrug systems to be used for the delivery of certain drugs that have poor water solubility or/and have low bioavailability as well as synthesis of prodrugs for masking the bitter taste of the corresponding parent drugs. The design will be executed using ab initio, DFT, semiempirical, molecular mechanics as well as molecular dynamics and conformational dynamics methods. The overarching goal of his research activities is to establish a method for obtaining prodrugs that their interconversion rates will be controlled or programmed by the linker nature attached to their parent drugs. Professor Karaman has more than 120 peer-reviewed manuscripts and book chapters; 60 of them were published in the recent 6 years. He is currently an editor and an editorial board member of 15 international journals in the areas of pharmaceutical sciences.

Research Interests

Design, synthesis, characterization and in vitro and in vivo kinetics of pro-prodrug systems to be used for the delivery for certain drugs that have poor water solubility or/and have low bioavailability using ab initio, DFT, semiempirical, molecular mechanics as well as molecular dynamics and conformational dynamics methods.

Design and synthesis of linkers to be used for masking bitter taste of drugs that contain a hydroxyl or amine groups (antimalarial, anti-hypertension, anti-bleeding, antibacterial and anticancer drugs, using DFT calculation methods.

Design and synthesis of bitter taste antagonists for inactivation of the bitter taste receptor 14.

Pharmaceuticals removal from wastewater using clay micelle complex, hollow fiber, spiral wounds, charcoal and other adsorbents.

Pharmaceuticals removal from wastewater using photodegradation methods such as light/TiO2.

Stability of Pharmaceuticals in wastewater and isolation and characterization of degradation products (metabolites).

Publications
Scientific Activities

Rashmi MadhuriPhd

Assistant Professor
Applied Chemistry
Banarus Hindu University
Address:India
Biography

Rashmi Madhuri is currently working as Assistant professor, Department of Applied Chemistry at Indian School of Mines, Dhanbad. She has obtained her Ph.D. degree from Banaras Hindu University, Varanasi. Currently, she is supervising seven full-time Ph.D. scholars, 3 Masters Students and authored above 40 reputed peer-reviewed journals with several book and book chapters. Her current research area is focused on the preparation of cost-effective next-generation smart nanomaterials for biomedical/sensor applications.

Research Interests

Molecularly imprinted polymer: Synthesis, characterization and application.
Nanotechnology: In the field of drug delivery.
Electrochemical sensors: For the ultra trace level estimation of biomolecules.

Publications
Scientific Activities

Rodrigo Portes UreshinoPhD


Department of Pharmacology
Federal University of Sao Paulo
Address:Brazil
Biography

Bachelor in Biomedicine in São Paulo State University (Brazil) in 2005. Dr. Ureshino received his Ph.D. in Pharmacology in Federal University of São Paulo (Brazil) in 2012. Dr. Ureshino aimed to investigate the metabolic alterations, such as calcium signaling and mitochondria function, of aged brain upon the inhibition of a tumor suppressor protein p53. He is currently a postdoctoral fellow in the Department of Pharmacology in Federal University of São Paulo (Brazil).

Research Interests

My research interest focus on the biology of aging, investigating changes in cellular homeostasis and the events that underlie cell fate, particularly apoptosis and autophagy. My research is based on investigations of calcium signaling alterations, oxidative stress, mitochondrial function, autophagy, and apoptotic proteins expression in aging brain, specifically in the striatum. Understanding the aging process and the molecular mechanisms of longevity may help prevent age-related diseases and/or improve the quality of life.

Publications
Scientific Activities

Shuo XiaoPhD

Postdoctoral Fellow
Department of Obstetrics and Gynaecology
Northwestern University
Address:China
Biography

Dr. Xiao earned his MD in Peking University Health Science Center in 2008, and then received his Ph.D. from University of Georgia in 2013. His Ph.D. dissertation focused on the molecular mechanism of embryo implantation and reproductive toxicology about the endocrine disruptors on female reproductive system. After his Ph.D. study, he joined Dr. Woodruff’s lab in Northwestern University as a postdoctoral fellow. His current research interest is to establish the 3D in vitro follicle culture using alginate hydrogel system for rodents, bovine, non-human primate and human, provide the fertility preservation options for young cancer patients, and how to improve the in vitro fertilization rate and quality using non-invasive markers. Until 2014, Dr. Xiao has 16 peer-reviewed papers and more than 30 conference abstracts published.He is the member of Endocrine Society, Society of Toxicology and Society for the Study of Reproduction.

Research Interests

His current research interest is to establish the 3D in vitro follicle culture using alginate hydrogel system for rodents bovine, non-human primate and human, provide the fertility preservation options for young cancer patients and how to improve the in vitro fertilization rate and quality using non-invasive markers

Publications
Scientific Activities

Sriram Chandra Shekhar

Research Associate
Department of Pharmacology & Toxicology
NIPER
Address:India
Biography

I’ve received M.S (Pharm) in Pharmacology & Toxicology, in 2012 from National Institute of Pharmaceutical Education and Research (NIPER), Guwahati, Assam, India. After completion of my Masters I’ve joined NIPER, Guwahati itself as a Research Scholar. I am a Pre-Clinical Pharmacology studies trainer in the institution. I have my proficiency in all most all the Central Nervous System animal models. In addition I usually train the students of the institution in performing animal behavioral studies for evaluating anti-depressant, anxiolytic, Parkinson’s and Alzheimer’s drugs. My research interest is to evaluate the poly (ADP-ribose) polymerase-1 inhibitors application in various central nervous system implications as well as other indications. Presently I am working on the exploration of PARP-1 inhibitors in chemical induced animal depression models. Mean while I am going to be awarded with Doctoral Degree in Pharmacology from NIPER, Guwahati by October, 2015.

Research Interests

Exploration of poly (ADP-ribose) polymerse-1 impact in central nervous system indications.

Publications
Scientific Activities

Tejraj M. AminabhaviPhD

Professor Emeritus and Research Director
Soniya College of Pharmacy
University of Texas
Address:India
Biography

Professor Tejraj M. Aminabhavi, received his PhD degree from the University of Texas at Austin in 1979 and subsequently, was a postdoctoral fellow at Clarkson University in 1980-82. Aminabhavi was a visiting professor to various universities in the US, Taiwan, UK, Korea and France. He had held several academic positions like the Director of Center of Excellence in Polymer Science at Karnatak University, Dharwad, India, Emeritus fellow from the CSIR and AICTE organizations, New Delhi, India and was a scientific adviser to Reliance Life Sciences, Mumbai, India. Aminabhavi has published 600 papers including authoritative review papers of high standing and has worked extensively in areas like pharmaceutics, polymer science, membranes and drug delivery. He is the most widely cited scientist with an H index of 67 and citations exceeding 20,000. Presently, Aminabhavi is the associate editor of Chemical Engineering Journal (Elsevier) and has been serving as advisory member on several international journals.

Research Interests

Molecular transport, membrane-based separations, pervaporation, gas separation, electrodialysis, micro, ultra and nanofiltrations and reverse osmosis.

Controlled release polymeric micro/nanoparticles, transdermal patches and hydrogels for drugs, proteins, peptides, genes, and pesticides.

Molecular modeling on polymer surfaces, QASR and docking studies on small molecules, prediction of polymer blend compatibility, drug diffusion and gas transport.

Polyurethane coatings, polymer composites, heat resistant and conducting polymers.

Liquid state properties, polymer solution theories and metal complexation chemistry.

Publications
Scientific Activities

Glenn S TillotsonPhD

Senior Partner
TranScrip Partners

Address:USA
Biography

Trained in medical microbiology and infectious diseases in the UK Glenn Tillotson has almost 30 years pharmaceutical experience in various areas including early pre-clinical and clinical research, commercialization, medical affairs, scientific communications including publication planning ,strategic drug development, life cycle management and global launch programs. Dr Tillotson has been instrumental in the development and launch of ciprofloxacin, moxifloxacin, gemifloxacin and other antibacterials. Dr. Tillotson became the Head of Medical Affairs at ViroPharma Incorporated where he oversaw educational, publication and other related activities for Vancocin, maribavir and Cinryze. In 2011 he joined Optimer Pharmaceuticals as Senior Vice President of Medical Affairs and built a 15 member team to support the launch of fidaxomicin (Dificid). Since 2012 he has been a Senior Partner at Transcrip-Partners in the USA. .He has been a member of the Scientific Steering Committee for the GTCBio Annual Summit on Anti-infective Partnering for the past 7 years. Additionally he is an Associate Editor of the journal for the Anaerobe Society of the Americas. Currently Dr Tillotson has published over 140 peer-reviewed manuscripts, presented >270 scientific posters and is on several journal Editorial Advisory Boards including the Lancet Infectious Disease, eBioMedicine and F1000.

Research Interests

Antibacterial resistance
Novel mechanisms to overcoming bacterial resistance
Impact of pharmacodynamics and resistance selection
Quality of generic antibiotics 

Publications
Scientific Activities

Moussa Ahmed




Address:
Biography
Research Interests
Publications
Scientific Activities