1999 S. Bascom Avenue, Suite 700, Campbell, CA, 95008, USA
Aperito Journal of Recent Trends in Genomics and Proteomics
Postdoctoral Research Associate
Donald Danforth Plant Science Center Address:USA
Dr. Md Shamimuzzaman is currently a postdoctoral research associate at the Donald Danforth Plant Science Center, Missouri, USA. He received his Ph.D. in Crop Sciences from the University of Illinois at Urbana-Champaign. His major research areas include plant molecular biology, biotechnology and genomics. He has experiences working on many crop plants such as potato, soybean and maize. He has published a number of articles on gene regulation during soybean seed and seedling development. His research findings were published in PNAS, Plant Physiology, BMC Genomics, Functional and Integrative Genomics. Currently he is working on the gene regulation during maize inflorescences development.
Dr. AzatMukhametovis a scientistin the fields of Computational/Physical Chemistry, Chemo- and Bioinformatics, and Molecular Modeling for Life Sciences. His research is devoted to application of computer technologies to bio-molecular and drug discovery challenges.
During his career, Dr. AzatMukhametov has experienced in application of multiple commercial and open-source software to drug design, molecular modeling, virtual screening, molecular dynamic simulations, docking studies, homology modeling, and binding energy calculations. He is of the mind that computer technologies are the future of drug discovery, and his goal is to use them for creating real medicines.
He defended his Ph.D. degree in 2009 (Physical Chemistry, thesis Design of chemical compounds with anti-inflammatory properties by the method of the theory of pattern recognition).Had special post-graduate training in Germany financed by Honor Stipendium from the President of Russian Federation, in subject â€œHomology modeling of molecular structures of active and inactive conformations of Myt1 and Wee1 kinase, docking of ligands, MD simulations, and MM PB/GBSA free energy calculationsâ€.During a postdoctoral training at the Centre of Chemical Biology (UniversitiSainsMalaysia), he applied methods of virtual screening, binding free energy calculations, and molecular modeling to study molecular mechanism of inhibition and discovery of new antiviral compounds against dengue and chikungunya viruses. At these days Dr. AzatMukhametovserves for an international pharmaceutical enterprise; at this role he provides consultancy and scientific support services to pharmaceutical and biotech companies, academic and non-profit institutions, and governmental bodies in the fields of his expertise.
Dr. AzatMukhametovhas received multipleawards for achievements in scientific research: Postdoctoral Fellowship Award from the University Sains Malaysia, Malaysia (2010-2013), Governmental Grant from the Government of the Republic of Bashkortostan, Russian Federation (2008), Honor Stipendium from the President of Russian Federation (2007), Honor Ministry Stipendium from the Ministry of Natural resources of the Republic of Bashkortostan of Russian Federation (2007), Laureate of Nation-wide Competition for the best scientific work on medicinal chemistry among young scientists from the countries of former USSR (2007), Postgraduate Stipendium from the Ministry of Education of Russian Federation for postgraduate study (2005 â€“ 2009).
Dr. AzatMukhametov is interested in design of bioactive chemical structures (chemicals and biologicals) with targeted properties
study, modeling, and simulation for life science molecular systems, macro- and micro- molecules
computational support for laboratory projects
catalytic and biophysical properties optimization for protein structures;
prediction of pharmacological activity and ADME
full-cycle technologies from target to drug prototype
design and developing of network and desktop applications for life sciences laboratory validations and support for drug discovery projects.
Department of Genetics
Harvard Medical School Address:USA
Dr. Chi Zhang is currently a research scientist with Dr. George Church at the Department of Genetics, Harvard Medical School. Dr. Zhang received his bachelor’s degree from Tsinghua University, Beijing, and performed his PhD work with Dr. Azad Bonni at Department of Neurobiology, Harvard Medical School. His PhD thesis focused on the pathophysiological mechanisms of cognitive impairments in intellectual disability, using a wide range of approaches including developmental neurobiology, biochemistry, functional genomics, mass spectrometry-mediated proteomics etc. Currently he is working on developing sequencing-based proteomic methods to study neuronal plasticity.
Mass spectrometry-mediated proteomics
Department of Animal Science
National Chung Hsing University Address:South America
Dr. San-Yuan Huang received his Ph.D in 1999 from National Chung Hsing University, Taiwan. He was the principal investigator of Laboratory of Proteomics and Molecular Genetics, Animal Technology Taiwan from January 2000 to July 2006. He then moved to the Department of Animal Science, National Chung Hsing University, Taiwan in August 2006 and established the Laboratory of Animal Proteomics. He has published more than 40 papers in international journals. His present research works lie in the area of animal proteomics and molecular genetics.
Thermotolerance in animals
Analysis of functional genomics in reproduction of animals
Assessment of the effect of nanoparticles on animals
Department of Environmental and Occupational Healt
National Cheng-Kung University-College of Medicine Address:Taiwan
Dr.Pao-Chi Liao is a Distinguished Professor at the Department of Environmental and Occupational Health (DEOH) from National Cheng-Kung University (NCKU), Taiwan. After completing his B.S. in Chemistry and M.S. in Chemical Engineering from National Tsing-Hua University, Taiwan, Dr. Liao received his Ph.D. in Analytical Chemistry from Michigan State University (MSU) in 1995. Dr. Liao joined the faculty at DEOH, NCKU-College of Medicine, Taiwan in 1997, where he was promoted to full professor in 2006, and named Distinguished Professor in 2011. Dr. Liao established and became the director for the Proteomics and Metabolomics Research Core Laboratory (PMRCL) and the Analytical Laboratory for Trace Environmental Pollutants (ALTEP) at NCKU. He is currently serving as the President of Taiwan Proteomics Society.
environmental and occupational health
Molecules with anticancer activity.
Molecules with GABA-ergic activity (prodrugs).
Molecules with antiviral activity.
Molecules with antibacterial activity and antiamebica.
Molecules with antagonist activity and / or agonist of serotonin receptors.
New inhibitors dell'HLE.
Analogs of anandamide. (Agonists / antagonists of CB1 and CB2 receptors andinterfering enzymes of the endocannabinoid system).
Inhibitors of PDE.
Heterocyclic compounds and metal-organic: synthetic studies and cytotoxicity.
New carbazoles activities iSTAT3.
Synthesis of new heterocyclic compounds with activity on the CNS (Alzheimer)
School of Pharmacy
Shanghai University of Traditional Chinese Medicin Address:China
Professor Hong-Xi Xu is currently the professor and the Dean of the School of Pharmacy, Shanghai University of Traditional Chinese Medicine. Prof. Xu has published more than 200 SCI papers, and obtained one PCT patent and six US patents. Prof. Xu obtained his Ph.D degree in Pharmaceutical Sciences in 1994 from Japan Toyama University. He has previously served as the Scientific Officer in the Institute of Chinese Medicine at the Chinese University of Hong Kong, the Deputy General Manager of Hutchison Whampoa (China) Ltd, the Board of Director and R & D Director at Shanghai Hutchison Pharmaceuticals. From 2001 to 2010, he served as the Deputy Director of Hong Kong Jockey Club Institute of Chinese Medicine. His major social appointments include: the Vice-President of The Foundation Conference of TCM Pharmaceutical Analysis Specialty Committee of the World Federation of Chinese Medicine, the Co-Chairman of International Conference of the Modernization of Chinese Medicine (ICMCM). He is also currently the Editorial Board Member of more than 10 scientific journals.
drug discovery from natural resources the development of botanical dietary supplements from herbal medicines
Cheorl-Ho KIM PhD
Department of Biological Science,
Sungkyunkwan University, Address:Korea
Prof/Dr Cheorl-Ho Kim has received his PhD in The University of Tokyo during the period of 1985-1990. Currently, he is working as professor in Department of Biological Sciences, College of Science, Sungkyunkwan University. He has successfully completed his Administrative responsibilities as Genome Program Head, Korea Research Institute of Bioscience and Biotechnology on 1990-1996 and Chairman, Department of Biochem and Molecular Biology, COM. DGU during 1996-2006. His research has included the oncognenesis, cancer metastasis and angiogenesis. Based on this research and fellowship training he has received several awards and honors, such as: National Science Medal and Academic Societies awards. He is serving as an editorial member of several reputed journals. He has authored 328 research articles/books. He is a member of International Scientific Advisory Board Member, International Symposium for Glycosyltransferases (GlycoT 2006), IUBMB symposium, Tsukuba and International Symposium for Glycosyltransferases (GlycoT 2008), Emory University, GA, USA, and International Biochemical and Molecular Engineering 2013, San Antonio, TX, USA.
Embryonic carbohydrate glycomics
Adhesion and angiogenesis
Mohamed Ahmed Abdel-Rahman Hassanein
Department Faculty of Science
Suez Canal University Address:Egypt
Mohamed A. Abdel-Rahman (PhD), Assistant Professor, Zoology Department, Faculty of Science, Suez Canal University, Egypt. In 2007, I have obtained my PhD degree (molecular physiology & toxinology) from Suez Canal University & Okayama University (Japan). Subsequently I awarded several postdoctoral fellowships in the UK & Mexico funded from the Egyptian Government, Arab Fund for Economic & Social Development (Kuwait), The Third World Academy of Science (TWAS, Italy), the Company of Biologists (Cambridge) and the Academy of Biomedical Sciences (London).
The biochemical & pharmacological examination of Egyptian animal venoms with a particular focus on toxins with neurotoxic, cytotoxic and cardiovascular activity
Molecular characterization of antimicrobial, anticancer peptides and ion channel neurotoxins from scorpions, snakes and Conus using different proteomic and transcriptomic approaches
Discovery of novel antimicrobial peptides from the venom of Egyptian desert scorpions
University of Maryland at College Park, MD/ARS-USD Address:USA
A Self-initiating scientist/academic with more than eight years experience in biology, microbiology, biotechnology, protein chemistry and proteomics including protein separation by gel-free (MudPIT, ICAT. iTRAQ, TMT) and gel based proteomics (IPG strip based 2-DE, DiGE) and their analyses by mass spectrometry in three developed countries: Japan, Australia and the USA. A broad experience in solving biological problems associated with environmental and salmonella associated food safety, protein-degradation, protein-lipid interaction, biofilm development in bacteria, risk in genetically modified organisms and plant-microbial interactions. Experienced in teaching and supervising students, writing successful grants and publishing scientific articles.
Medical University of South Carolina Address:Charleston SC USA
Venkateh is a postdoctoral scholar at Medical University of South Carolina, Charleston, USA. He is expertise in proteomics, cancer biology, ceramide biology and RNA biology.
Kota V, Dhople VM, Fullbright G, Smythe NM, Szulc ZM, Bielawska A, Hama H. (2013) 2'-hydroxy C16-ceramide induces apoptosis-associated proteomic changes in C6 glioma cells. J. Proteome Res. 12, 4366-4375.
Kota V, Szulc ZM, Hama H. (2012) Identification of C6-ceramide-interacting proteins in D6P2T Schwannoma cells. Proteomics 12, 2179-2184.
Rai P, Kota V, Sundaram CS, Deendayal M, Shivaji S. (2010) Proteome of human endometrium: Identification of differentially expressed proteins in proliferative and secretory phase endometrium. Proteomics Clin. Appl. 4, 48-59.
Rai P, Kota V, Deendayal M, Shivaji S. (2010) Differential proteome profiling of eutopic endometrium from women with endometriosis to understand etiology of endometriosis. J. Proteome Res. 9, 4407-4419.
Kota V, Rai P, Weitzel JM, Middendorff R, Bhande SS, Shivaji S. (2010) Role of glycerol-3-phosphate dehydrogenase 2 in mouse sperm capacitation. Mol. Reprod. Dev. 77, 773-783.
Kameshwari DB, Bhande S, Sundaram CS, Kota V, Siva AB, Shivaji S. (2010) Glucose-regulated protein precursor (GRP78) and tumor rejection antigen (GP96) are unique to hamster caput epididymal spermatozoa. Asian J. Androl. 12, 344-355.
Kota V, Dhople VM, Shivaji S. (2009) Tyrosine phosphoproteome of hamster spermatozoa: role of glycerol-3-phosphate dehydrogenase 2 in sperm capacitation. Proteomics 9, 1809-1826.
Kumar V, Kota V, Shivaji S. (2008) Hamster sperm capacitation: role of pyruvate dehydrogenase A and dihydrolipoamide dehydrogenase. Biol. Reprod. 79, 190-199.
Kota V, Hama H. (2014) 2'-Hydroxy ceramide in membrane homeostasis and cell signaling. Adv. Biol. Regul. 54, 223-230.
Shivaji S, Kota V, Siva AB. (2009) The role of mitochondrial proteins in sperm capacitation. J. Reprod. Immunol. 83, 14-18.
Dana-Farber Cancer Institute Address:USA
Dr. Jing Zhang received her bachelor’s degree from University
of Science and Technology of China, and her PhD in Chemical
Biology from Harvard University. Her research has included the
mechanisms of carcinogenesis, drug resistance, and the
development of novel targeted cancer therapies. Dr. Zhang has
extensive experience in deciphering oncogenic signal
transduction pathways using a wide range of approaches
including biochemistry, cell biology, genomic and proteomic
Tumorigenesis and metastasis
Ali M ArdekaniPhD
Department of Medical Biotechnology
National Institute of Genetic Engineering and Biotechnology Address:Shahrake Pajoohesh,
Dr. Ali M. Ardekani obtained his B.Sc. and M.Sc. degrees from Western Illinois University, Illinois, U.S.A. in 1981 and 1984, respectively. His Ph.D. degree in the field of Genetics and Developmental Biology was completed in 1988 at West Virginia University, West Virginia, U.S.A. He returned to Iran after completion of his post-doctoral training in Genetic Engineering and Biotechnology in 1992 and was appointed as an Assistant Professor at the Pasteur Institute of Iran where he helped the establishment of biotechnology department.
After two years he returned to the U.S. and began his studies on gene regulation at the transcriptional levels in the departments of Radiation Oncology and Molecular Biology at the University of Pittsburgh and Northwestern University, respectively. Finally in 1999, he joined the FDA/NCI Clinical Proteomics Center at the National Institutes of Health (NIH) at Bethesda, Maryland in the U.S. During his stay at NIH, he was a leading member of the research team which produced the landmark article on the use of Proteomics patterns in the serum of ovarian cancer patients as an early detection method. This article was published in the Journal “Lancet” and has received more than 3300 citations up to now.
Currently he is an Associate Professor at the National Institute of Genetic Engineering and Biotechnology in Iran. He is the recipient of 2012 grant from International Center for Genetic Engineering and Biotechnology (ICGEB) for the amount €42,000 grant to conduct research on the role of DNA methylation as an early change marker in several genes associated with breast cancer in young women from the Northern region of Iran. He is currently holding several leadership positions including the “Director” of ‘Middle Eastern association for Cancer Research (MEACR)’ http://www.meacr.org/ for the past 2 years.
He has published more than 50 peer-reviewed articles and four books in Persian language and is a member of the Iran National Cancer steering Committee and a founding member of the Iranian society for Health Genomics and Biotechnology. He was the founder and the first editor of Avicenna Journal of Medical Biotechnology and currently is an Associate editor of the Iranian Journal of Biotechnology in the field of Medical Biotechnology.
Clinical Proteomics and Mass Spectrometry Group
University Medical Center Goettingen Address:Germany
PD Dr. Abdul Rahman Asif isassociate professor of molecular medicine and director research at the Institute of Clinical Chemistry, University Medical Center Göttingen (UMG). Beside this, he is responsible for various diagnostic units at the UMG-laboratories. Dr. Asif has extensive experience in the field of clinical proteomics, in particular differential proteomics,target elucidation and characterization of PTM. His research group is collaborating with several national and international partners in wide range of clinical research topics. His teaching activities encompass a range of molecular medicine topics and investigative diagnostics. He has authored and co-authored more than 60 peer reviewed articles on clinical proteomics and molecular medicine.
Diagnostics, prognostics and therapy monitoring marker for cardiovascular diseases
Identifying novel molecular targets of drugs
Protein - protein and protein – drug interactions
Immuno-proteomics for identification of new diagnostic and vaccine targets
Paul Brousse hospital Address:France
In October 2012, I have received my PhD at Burgundy University in France after performing my research activities at the proteomic platform of the Department Environment and Agro-biotechnologies of the CRP-Gabriel Lippmann in Luxembourg and INRA 1347 in Dijon, France.
My PhD fields of interest were proteomics in relation with plant responses to environmental constraints and development of innovative shotgun proteomic frameworks for identification of recalcitrant proteins. Membrane proteomics is still challenging due to 2-DE related shortcomings, however latest trends and advancements in mass spectrometry (MS)-based quantitative proteomics offer enormous potential to monitor membrane protein change in abundance in large scale experiments. During my PhD, microsomal proteins of Medicago truncatula roots inoculated with Rhizophagus irregularis were, for the first time, scrutinized by state-of-the-art MS-based proteomic approaches iTRAQ-OFFGEL-LC-MS/MS and label-free 1-DE-LC-MS/MS. The applied workflows combined two novel proteomic procedures, label-based and -free targeting an insight view on the membrane proteome changes in arbuscular mycorrhizal (AM) symbiosis. In addition to the biological gain by shedding the light on candidate AM-related membrane proteins, a methodological approach was carried out in order to elucidate the iTRAQ labelling impact on peptide isoelectric points.
Since December 2012, I was hired as post-doctoral fellow at INSERM U785 at Paul Brouse hospital in Villejuif, France. Infection with Hepatitis C virus (HCV) is often persistent and can progress to liver cirrhosis and hepatocellular carcinoma. HCV core protein activates transforming growth factor (TGF-ß), a cytokine playing a paradoxical role as both tumor suppressor and tumor promoter. Phosphorylation activates and regulates the canonical TGF-ß signaling pathway, which raises the need of characterizing its phosphoproteome. However, protein phosphorylation occurs in a substoichiometry manner, making its detection and identification a challenging task. My current project aims at designing a state-of-the-art quantitative proteomic approach to shed the light on novel phosphoproteins involved in the adhesion-regulated signaling systems to collaborate with TGF-ß in mediating epithelial mesenchymal transition. Such a strategy will contribute to comprehensively understand the molecular mechanisms controlled by HCV core protein and the way they deregulate TGF-ß pathways. This approach will provide a powerful rationale for evaluation of TGF-ß signaling modulators for the identification targets and effective therapies in HCV pathologies.
Furthermore, I had the occasion to take part in several European meetings and conferences where I presented my research results either by giving an oral communication or presenting a poster.
Proteomics and Mass Spectrometry facility
University of Piemonte Orientale Amedeo Avogadro Address:Italy
Dr. Francesco Marsano is a research technician in Biochemistry and Proteomics at the University of Piemonte Orientale, Alessandria, Italy.
Prior to joining University of Piemonte Orientale worked for some years as temporary researcher at Universities of Genova and Milan.
At present Dr. Marsano leads the laboratory of proteomics and mass spectrometry at department of Science and Technological Innovation (DISIT), University of Piemonte Orientale, Italy.
He received his MS in Biology with honor from University of Genoa, and his PhD from University of Piemonte Orientale.
He resides in Genoa, Italy with his wife Paola, and his daughter Aurora.
Identify and quantify proteins
Mytilus galloprovincialis stress responses
Elucidate the Complex proteome of Photosystem II
Characterize metabolites both in animal and plant cells and tissues
Identify small natural dye molecules
National Institute of Mental Health
Dr. Hongbao Cao received the B.E. and M.S. degrees in biomedical engineering from the College of Precision Instrument and Optoelectronics Engineering, Tiangjin University,Tianjin,China, in 2002 and 2005, respectively. He received the Ph.D. degree from the Biomedical EngineeringDepartment, Louisiana Tech University, Ruston, USA. He was a Postdoctoral Research Associate with the Department of Electronic Engineering and Computer Science, University of Missouri, Kansas City (2009-2010) and Postdoctoral Research Associate with the Department of Biomedical Engineering, Tulane University (2010-2012). He has over 40 publications, and his research interests involve signal processing, image processing, pattern recognition, and computational modeling. He is currently working at National Institutes of Health (NIH), USA. His present research is developing computational models for combined analysis of complex disease using different data modality, such as Schizophrenia, Bipolar disorder, and autism.
Hossain Mohammad AyazPhD
Georges University of London Address:UK
My academic transplantation career started with my first LAT ST3 post at St Georges Hospital where I was able to participate in the Warm Ischaemia research of Mr Rene Chang. I presented internationally then at the World Transplant Congress 2008, Sydney Australia our preliminary results and with good feedback the project developed into the later work of my PhD.
I have now submitted my thesis with St Georges University of London having forged connections around London with laboratories at Kings College Hospital, UCL and Queen Elizabeth Hospital. My future research interests lie in renal ischaemia reperfusion injury and mesenchymal stem cell use. I have developed skills in proteomics and genomics. My immediate aim is follow an academic career through the NIHR lectureship whilst completing my clinical training. My eventual aim is pursue an academic chair in a renal transplant unit aiming its research goal in warm ischaemia and reperfusion injury.
Renal ischaemia reperfusion injury
Mesenchymal stem cell use
Department of Applied Science
National Chiao Tung University Address:Taiwan
Dr Hsiu-Chuan Chou is currently working as an Associate Professor at National Hsinchu University of Education in Taiwan since 2013. Dr. Chou received her PhD degree from King’s College, University of London in 2005. After 2 year post-doctoral training in the Cell Motility and Cytoskeleton research section in the Randall Division, she took a Researcher offer at Biomedical Laboratories in Industrial Technology Research Institute of Taiwan to develop therapeutic stem cells and diagnostic MRI nanoparticles for 3 years. Later on, Dr. Chou is moving into academic research labs with strong collaborative ties to biotech companies and hospitals. Dr. Chou’s group focuses on: immune cell migration, podosomes dynamics, MRI nanoparticle validation as well as proteomic approaches for the phenotypic hallmark traits and cellular signaling pathways in targeting toxic effect and drug resistance of cancer treatment.
Immune cell migration
MRI nanoparticle validation
Proteomic approaches for cancer biomarker discovery
Cellular signaling pathways
Dept. Genomic Medicine
Changhua Christian Hospital Address:Changhua
Prof. Chen is an obstetrician, geneticist(both basic mammalian and medical human), and fetal medicine specialist. He had published more than 80 peer-review journal papers (since 1999) including some of them being regarded as important worksin their fields related to non-invasive prenatal diagnosis (NIPT), preimplantation genetic diagnosis (PGD), array CGH/molecular and cytogenetics, fetal therapy, and evolutionary comparative genomics, which were published inUltrasound ObstetGynecol, Gene, Zoology, PLoS ONE, Am J Med Genet, Prenatal Diagnosis, Fertility and Sterility, and Theriogenology. Dr. Chen’s lab is the first and the only one in Taiwan at the moment passed the accreditation by College of American Pathologists (CAP) independently as a diagnostic clinical genetic laboratory. He holds an honorary associate professorship in National Taiwan University College of Medicine. Dr. Chen is an Orthodox Christian.
Department of Horticulture
Gyeongsang National University Address:Jinju,
Dr. Sowbiya Muneer is currently Research Professor at the Institute of Agricultural Sciences, Department of Horticulture, Gyeongsang National University, Korea. After completing M.S. in Botany from Jamia Hamdard University, New Delhi, India in 2007. Dr. Muneer received her Ph. D in Plant Biotechnology from Jamia Millia University, New Delhi, India in 2011. She then worked in Pohang university of Science and Technology (POSTECH) and Chonnam National University, Korea, as a Postdoctoral Researcher from 2011-2014. Her research work mainly focusses in the area of Plant Proteomics and Plant Molecular physiology.
Plant Molecular Physiology
Université de Mons Address:6 av du Champs de Mars
Dr. Ruddy Wattiez is leading the proteomics and microbiology group (ProtMic) at the Research Institute for Biosciences, UMONs. Actually, the group consists of 1 professor, 1 associated professor, 1 assistant professor, 3 postdocs, 10 Ph.D. students and 1 technician (http://w3.umons.ac.be/~protmic/index.htm). The Proteomics and Microbiology (ProtMic)’ group (R. Wattiez), initiated in 2007, focuses on functional/structural proteomics and protein chemistry, especially in the microbiology area. He developed quantitative proteomic approach associated to microbial world such as metaproteomic approach.
Department of Biochemistry,
Mersin University, Address:Mersin,
Prof. Serap Yalin currently is the Professor of Biochemistry and the head of Biochemistry Department at the Pharmacy Faculty of Mersin University. She received her Ph.D. from the Medical Faculty of Çukurova University. Her scientific interests include: Free radicals, hemolytic anemias, polymorphism, protein chemistry, recombinant antibody production. She is an Associate Editor of African Journal of Biochemistry Research and Review Editor of Frontiers in Genomic Assay Technology. She is a member of the Editorial Board in Open Journal of Blood Diseases, World Journal of Rheumatology, World Journal of Diabetes, International Journal of Medical Genetics and Genomics Research, Prime Research on Medicine, International Journal for Biotechnology and Molecular Biology Research, International Journal of Medicine and Medical Sciences. She has European Association of Cancer Research (EACR) Travel Fellowship.
Erythrocyte membrane proteins
Sickle cell anemia
G6PD enzyme deficiency
Protein isolation, Purification
Recombinant antibody production
CYP-450 enzyme system
Department of Nano-Medicine
Houstan Methodist Research Institute Address:6670 Bertner Street,R8-430,
Since being a Ph.D. study in Peking Union Medical College,Tsinghua University, China in 2003 to 2008, Dr. Li have received a very comprehensive training focused on proteomics technology, including the basic concepts, experimental skills, application experiences on mass spectrometry and bioinformatics methods. From 2009 to 2011, as a research associate in The Hong Kong University of Sci. & Tech., Dr. Li established an absolute and quantitative phosphoproteomics platform and published this work on the top journal in proteomics field - Molecular & Cellular Proteomics. After joining Dr. Mauro Ferrari’s lab as a postdoc in 2012, Dr. Li have been engaged myself in circulating peptidomicsand biomarker study on major human diseases, includingcancers and infectious diseases. Dr. Li have conducted a study representing a first demonstration that clearly links the proteolytic activity of proteases, particularly at disease sites, to the cleavage patterns of its catalytic substrates in the blood, by means of a rapid, reproducible, sensitive, precise and non-invasive approach. An editorial article about our study, written by a pioneer scientist in proteomic field - Dr. Eleftherios P. Diamandis from Univ. of Toronto, was published together with this report on the same issue of Clinical Chemistry in 2014.
Biomarker discovery and detection
Pursuing unknown circulating protein/peptide biomarker for multiple types of cancers
Isolate low-molecular-proteins from human body fluids
Quantitative proteomics/ peptidomics techniques
Aiming at high sensitivity and high specificity detection strategy of well-known biomarkers